Latest publications

Publication of various scientific studies

April 05 - 2024

Identification of Cellular Protein Targets of a Half-Sandwich Iridium(III) Complex Reveals Its Dual Mechanism of Action via Both Electrophilic and Oxidative Stresses (Équipe Prunier)

J Med Chem. 2024 Apr 25;67(8):6189-6206 Identification of intracellular targets of anticancer drug candidates provides key information on their mechanism of action. Exploiting the...

March 29 - 2024

Features of cryptococcosis among 652 HIV-seronegative individuals in France: a cross-sectional observational study (2005-2020) (Équipe Seksik/Sokol)

Clin Microbiol Infect. 2024 Mar 29:S1198-743X(24)00162-9 OBJECTIVES : We aimed to describe features and outcomes of cryptococcosis among HIV-seronegative individuals in a large...

March 07 - 2024

Molecular epidemiology of Candida africana isolates collected from vagina swabs in French Guiana (Équipe Seksik/Sokol)

Med Mycol. 2024 Mar 7;62(3):myae016 Previous molecular studies have shown that Candida africana corresponds to the clade 13 of Candia albicans. It has been mostly involved in...

March 07 - 2024

[Antimicrobial peptides: A new alternative for the treatment of aspergillosis] (Équipe Seksik/Sokol)

Rev Mal Respir. 2024 Apr;41(4):283-288 Aspergillus fumigatus is the predominant fungal species causing pulmonary aspergillosis. The present-day anti-aspergillosis arsenal is limited,...

November 14 - 2023

Adipocyte glucocorticoid receptor activation with high glucocorticoid doses impairs healthy adipose tissue expansion by repressing angiogenesis (Équipe Fève)

Diabetes. 2023 Nov 14:db230165. doi: 10.2337/db23-0165 In Human, glucocorticoids (GC) are commonly prescribed because of their anti-inflammatory and immunosuppressive properties....

June 01 - 2023

Prediction of response to immune checkpoint blockade in patients with metastatic colorectal cancer with microsatellite instability (Team Duval)

Ann Oncol. 2023 Aug;34(8):703-713 BACKGROUND : Mismatch repair-deficient (dMMR) tumors displaying microsatellite instability (MSI) represent a paradigm for the success of immune...

January 08 - 2023

Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases (Équipe Gautheron/Housset)

Int J Mol Sci. 2023 Jan 8;24(2):1236 ABCB4 (ATP-binding cassette subfamily B member 4) is a hepatocanalicular floppase involved in biliary phosphatidylcholine (PC) secretion. Variations in...

December 29 - 2022

Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells (Équipe Netchine)

Clin Epigenetics 2022; 14: 190. BACKGROUND : Parental imprinting is an epigenetic mechanism that leads to monoallelic expression of a subset of genes depending on their parental origin....

December 06 - 2022

Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant Staphylococcus aureus to Human Group IIA-Secreted Phospholipase A2 and Daptomycin (Équipe Corvol)

J Innate Immun. 2022 Dec 6:1-18 Methicillin-resistant Staphylococcus aureus (MRSA) has been classified as a high priority pathogen by the World Health Organization underlining the high...

December 01 - 2022

Diversity of the nucleic acid forms of circulating HBV in chronically infected patients and its impact on viral cycle (Équipe Gautheron/Housset)

Hepatol Int 2022 Vol. 16 Issue 6 Pages 1259-1272 BACKGROUND : Besides the prototypical hepatitis B virus (HBV) infectious particle, which contains a full-length double-stranded DNA...
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France

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