Latest publications

Publication of various scientific studies

July 09 - 2018

Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes (Équipe Seksik/Sokol)

J Pathol. 2018;246(2):217-30 Obesity and its metabolic complications are characterized by subclinical systemic and tissue inflammation. In rodent models of obesity, inflammation and...

May 15 - 2018

Intraflagellar transport is deeply integrated in hedgehog signaling (Équipe Seksik/Sokol)

Mol Biol Cell. 2018;29(10):1178-89 The vertebrate hedgehog pathway is organized in primary cilia, and hedgehog components relocate into or out of cilia during signaling. Defects in...

April 07 - 2018

Aryl hydrocarbon receptor and intestinal immunity (Équipe Seksik/Sokol)

Mucosal Immunol. 2018;11(4):1024-38 Aryl hydrocarbon receptor (AhR) is a member of the basic helix-loop-helix-(bHLH) superfamily of transcription factors, which are associated with cellular...

July 18 - 2018

Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice (Équipe SeksikSokol)

Nat Commun. 2018;9(1):2802 Dietary lipids favor the growth of the pathobiont Bilophila wadsworthia, but the relevance of this expansion in metabolic syndrome pathogenesis is poorly...

March 01 - 2018

Glycerolipid analysis during desiccation and recovery of the resurrection plant Xerophyta humilis (Bak) Dur and Schinz (Équipe Seksik/Sokol)

Plant Cell Environ. 2018;41(3):533-47 Xerophyta humilis is a poikilochlorophyllous monocot resurrection plant used as a model to study vegetative desiccation tolerance. Dehydration imposes...

August 29 - 2018

Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota (Équipe Seksik/Sokol)

PLoS One. 2018;13(8):e0202587 Background and Aims : N-acyl homoserine lactones (AHLs), which are autoinducer quorum-sensing molecules involved in the bacterial communication network, also...

February 07 - 2019

TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function (Équipe Seksik/Sokol)

Gut. 2019 Objective : We explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA...

March 01 - 2019

The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases (Équipe Seksik/Sokol)

Nat Rev Gastroenterol Hepatol. 2019;16(6):331-45 The gut microbiota is a dense and diverse ecosystem that is involved in many physiological functions as well as in disease pathogenesis. It...

March 01 - 2019

Intestinal plasticity in response to nutrition and gastrointestinal surgery (Équipe Seksik/Sokol)

Nutr Rev. 2019;77(3):129-43 The plasticity of a material corresponds to its capacity to change its feature under the effect of an external action. Intestinal plasticity could be defined as...

March 08 - 2019

Genetic effects on the commensal microbiota in inflammatory bowel disease patients (Équipe Seksik/Sokol)

PLoS Genet. 2019;15(3):e1008018 Several bacteria in the gut microbiota have been shown to be associated with inflammatory bowel disease (IBD), and dozens of IBD genetic variants have been...
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