Latest publications

Publication of various scientific studies

October 12 - 2021

Risk factors for Pseudomonas aeruginosa airway infection and lung function decline in children with cystic fibrosis (Équipe Corvol)

J Cyst Fibros. 2021 Background Cystic fibrosis (CF) lung disease is characterised by recurrent Pseudomonas aeruginosa (Pa) infections, leading to structural lung damage and decreased...

September 25 - 2021

Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells (Équipe Sabbah)

Leukemia (2021) Myeloma is characterized by bone lesions, which are related to both an increased osteoclast activity and a defect in the differentiation of medullary mesenchymal stem cells...

September 16 - 2021

Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus (Équipe Dorothée)

Nat Rev Neurol. 2021 Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates that pathological alterations in...

September 01 - 2021

TFH cells in systemic sclerosis (Équipe Mohty)

cells in systemic sclerosis. J Transl Med 19 (2021): 375 Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis with progression to internal organs, vascular...

August 12 - 2021

Weak immunogenicity of SARS-CoV-2 vaccine in patients with hematologic malignancies (Équipe Mohty)

Blood Cancer J 11 (2021): 142 This study evaluated the safety and immunogenicity of BNT162b2 vaccine in patients with hematological malignancies. Antibodies blocking spike binding to...

August 08 - 2021

Osteopontin as a Regulator of Colorectal Cancer Progression and Its Clinical Applications (Équipe Sabbah)

Cancers (Basel) 13 (2021) A high expression of the phosphoprotein osteopontin (OPN) has been associated with cancer progression in several tumor types, including breast cancer,...

August 04 - 2021

EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence (Équipe Housset / Équipe Fève)

Elife. 2021;10. Epoxide hydrolases (EHs) regulate cellular homeostasis through hydrolysis of epoxides to less-reactive diols. The first discovered EH was EPHX1, also known as mEH. EH...

July 30 - 2021

Regulatory B cell imbalance correlates with Tfh expansion in systemic sclerosis (Équipe Mohty)

Clin Exp Rheumatol 39 Suppl 131 (2021): 20-24 OBJECTIVES : Systemic sclerosis (SSc) is an autoimmune disease with fibrosis, microangiopathy and immune dysfunction. B cell abnormalities...

July 21 - 2021

Impact of gut fungal and bacterial communities on the outcome of allogeneic hematopoietic cell transplantation (Équipe Mohty)

Mucosal Immunol 14 (2021): 1127-1132 Patients receiving allogeneic hematopoietic cell transplantation (alloHCT) were previously shown to display a bacterial gut dysbiosis; however, limited...

July 20 - 2021

Screening of patients born small for gestational age with the Silver-Russell syndrome phenotype for DLK1 variants (Équipe Netchine)

Eur J Hum Genet (2021) Silver-Russell syndrome (SRS) is a rare imprinting disorder associated with prenatal and postnatal growth retardation. Loss of methylation (LOM) on chromosome 11p15...
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