Latest publications

Publication of various scientific studies

September 27 - 2022

CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival (Équipe XXXX)

Gut. 2022 OBJECTIVES : Inflammatory bowel disease (IBD) results from a combination of genetic predisposition, dysbiosis of the gut microbiota and environmental factors, leading to...

September 16 - 2022

Cold plasma endoscopy applied to biliary ducts: feasibility risk assessment on human-like and porcine models for the treatment of cholangiocarcinoma (Équipe Gautheron-Housset)

Journal of Physics D: Applied Physics, Volume 55, Number 45 For the past 12 years, cold plasmas (i.e. weakly ionized gas) have been positioned as a breakthrough technology for treating...

September 13 - 2022

Unraveling the actin cytoskeleton in the malignant transformation of cholangiocyte biology (Équipe Gautheron/Housset)

Transl Oncol 2022 Vol. 26 Pages 101531 Correct actin cytoskeleton organization is vital in the liver organ homeostasis and disease control. Rearrangements of the actin cytoskeleton may play...

September 01 - 2022

Genetic alterations shaping tumor response to anti-EGFR therapies (Équipe Gautheron/Housset)

Drug Resist Updat 2022 Vol. 64 Pages 100863 The Epidermal Growth Factor Receptor (EGFR) has been targeted through the development of selective tyrosine kinase inhibitors (TKIs) and...

September 01 - 2022

EASL Clinical Practice Guidelines on sclerosing cholangitis (Équipe Gautheron/Housset)

J Hepatol 2022 Vol. 77 Issue 3 Pages 761-806 Management of primary or secondary sclerosing cholangitis is challenging. These Clinical Practice Guidelines have been developed to provide...

August 27 - 2022

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease (Équipe Gautheron/Housset / Fève)

Hepatology 2022 BACKGROUND AND AIMS : Receptor-interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the...

June 15 - 2022

Pollutants: a candidate as a new risk factor for osteoarthritis-results from a systematic literature review (Équipe Berenbaum)

RMD Open 2022; 8 BACKGROUND : Considering non-classical environmental risk factors for osteoarthritis (OA), a systematic literature review (SLR) was performed to summarise existing...

June 10 - 2022

IGF2: Development, Genetic and Epigenetic Abnormalities (Équipe Netchine)

Cells 2022 Vol. 11 Issue 12 Pages 1886 In the 30 years since the first report of parental imprinting in insulin-like growth factor 2 (Igf2) knockout mouse models, we have learnt much about...

June 09 - 2022

3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors (Équipe Seksik-Sokol)

Sci Rep 2022; 12: 9440 In the gut ecosystem, microorganisms regulate group behaviour and interplay with the host via a molecular system called quorum sensing (QS). The QS molecule...

June 09 - 2022

Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level (Équipe Berenbaum)

Nanoscale 2022; 14: 8691-8708 The extracellular matrix (ECM) of articular cartilage is a three-dimensional network mainly constituted of entangled collagen fibrils and interfibrillar...
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France

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