Latest publications

Publication of various scientific studies

May 23 - 2020

Cold-Atmospheric Plasma Induces Tumor Cell Death in Preclinical In Vivo and In Vitro Models of Human Cholangiocarcinoma (Équipe Housset)

Cancers (Basel). 2020;12(5) Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a...

January 09 - 2021

Cholangiopathy aggravation is caused by VDR ablation and alleviated by VDR-independent vitamin D signaling in ABCB4 knockout mice (Équipe Housset)

Biochim Biophys Acta Mol Basis Dis. 2021;1867(4):166067 BACKGROUND & AIMS : Cholangiopathies are chronic liver diseases in which damaged cholangiocytes trigger a proinflammatory and...

February 12 - 2021

Tryptophan metabolites get the gut moving (Équipe Seksik - Sokol )

Cell Host Microbe. 2021;29(2):145-7 How gut microbes can regulate the enteric nervous system and gut-brain communications is a field of intense research. In this issue of Cell Host &...

February 09 - 2021

Low-phospholipid-associated cholelithiasis syndrome: Prevalence, clinical features, and comorbidities (Équipe Housset )

JHEP Rep. 2021;3(2):100201 Background & Aims : Low-phospholipid-associated cholelithiasis (LPAC) syndrome, a rare genetic form of intrahepatic cholelithiasis in adults, is still poorly...

February 26 - 2020

Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis (Équipe Housset)

Dis Model Mech. 2020;13(4) Normothermic perfusion provides a means to rescue steatotic liver grafts, including by pharmacological defatting. In this study, we tested the potential of new...

March 10 - 2021

SARS-CoV-2 infection in nonhuman primates alters the composition and functional activity of the gut microbiota (Équipe Seksik - Sokol)

Gut Microbes. 2021;13(1):1-19 The current pandemic of coronavirus disease (COVID) 2019 constitutes a global public health issue. Regarding the emerging importance of the gut-lung axis in...

April 29 - 2021

Recipient factors in faecal microbiota transplantation: one stool does not fit all (Équipe Seksik - Sokol)

Nat Rev Gastroenterol Hepatol. 2021 Faecal microbiota transplantation (FMT) is a promising therapy for chronic diseases associated with gut microbiota alterations. FMT cures 90% of...

July 08 - 2021

Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal gammadelta T cells (Équipe Seksik - Sokol / Équipe Netchine)

Cell Rep. 2021;36(1):109332 Gut interleukin-17A (IL-17)-producing gammadelta T cells are tissue-resident cells that are involved in both host defense and regulation of intestinal...

August 04 - 2021

EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence (Équipe Housset / Équipe Fève)

Elife. 2021;10. Epoxide hydrolases (EHs) regulate cellular homeostasis through hydrolysis of epoxides to less-reactive diols. The first discovered EH was EPHX1, also known as mEH. EH...

December 11 - 2020

The differentiation of prehypertrophic into hypertrophic chondrocytes drives an OA-remodeling program and IL-34 expression (Équipe Berenbaum)

Osteoarthritis Cartilage 29 (2021): 257-268 OBJECTIVES : We hypothesize that chondrocytes from the deepest articular cartilage layer are pivotal in maintaining cartilage integrity and that...
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France

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