Latest publications

Publication of various scientific studies

March 08 - 2019

Genetic effects on the commensal microbiota in inflammatory bowel disease patients (Équipe Seksik/Sokol)

PLoS Genet. 2019;15(3):e1008018 Several bacteria in the gut microbiota have been shown to be associated with inflammatory bowel disease (IBD), and dozens of IBD genetic variants have been...

March 06 - 2019

Overgrowth syndromes - clinical and molecular aspects and tumour risk (Équipe Netchine)

Nat Rev Endocrinol. 2019;15(5):299-311 Overgrowth syndromes are a heterogeneous group of rare disorders characterized by generalized or segmental excessive growth commonly associated with...

March 01 - 2019

The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases (Équipe Seksik/Sokol)

Nat Rev Gastroenterol Hepatol. 2019;16(6):331-45 The gut microbiota is a dense and diverse ecosystem that is involved in many physiological functions as well as in disease pathogenesis. It...

March 01 - 2019

Intestinal plasticity in response to nutrition and gastrointestinal surgery (Équipe Seksik/Sokol)

Nutr Rev. 2019;77(3):129-43 The plasticity of a material corresponds to its capacity to change its feature under the effect of an external action. Intestinal plasticity could be defined as...

February 20 - 2019

Transcriptional profiling at DLK1/MEG3 domain explains clinical overlap between imprinting disorders (Équipe Netchine)

Sci. Adv. 2019; 5 : eaau9425 Clinical and molecular overlap in imprinting disorders Imprinting disorders (ID) often affect growth in humans, leading to diseases with overlapping...

February 11 - 2019

SERPINA1 Z allele is associated with cystic fibrosis liver disease (Équipe Corvol)

Genetics in Medicine 2019 Purpose : The SERPINA1 Z allele is associated with cystic fibrosis (CF)-related liver disease (CFLD), a common manifestation in patients with CF. We estimated...

February 07 - 2019

TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function (Équipe Seksik/Sokol)

Gut. 2019 Objective : We explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA...

February 01 - 2019

Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure (Équipe Fève)

Diabetes. 2019;68(2):305-17 Widely used for their anti-inflammatory and immunosuppressive properties, glucocorticoids are nonetheless responsible for the development of diabetes and...

January 11 - 2019

Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis (Équipe Berenbaum)

Arthritis Res Ther. 2019;21(1):18 Background : Accumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme...

January 10 - 2019

Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential (Équipe Seksik/Sokol)

Toxicol Sci. 2019;168(2):474-85 Drug-induced cholestasis is mostly intrahepatic and characterized by alterations of bile canaliculi dynamics and morphology as well as accumulation of bile...
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France

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