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October 12 - 2021

Risk factors for Pseudomonas aeruginosa airway infection and lung function decline in children with cystic fibrosis (Équipe Corvol) Julie Mésinèle, Manon Ruffin, Astrid Kemgang, Loïc Guillot, Pierre-Yves Boelle, Harriet Corvol

J Cyst Fibros. 2021 Background Cystic fibrosis (CF) lung disease is characterised by recurrent Pseudomonas aeruginosa (Pa) infections, leading to structural lung damage and decreased...
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BLANCHET-DEVERLY Sarah

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BLONDEAU Bertrand

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December 07 - 2021

Flagellin From Pseudomonas aeruginosa Modulates SARS-CoV-2 Infectivity in Cystic Fibrosis Airway Epithelial Cells by Increasing TMPRSS2 Expression (Équipe Corvol) Manon Ruffin, Jeanne Bigot, Claire Calmel, Julia Mercier, Maelle Givelet, Justine Oliva, Andres Pizzorno, Manuel Rosa-Calatrava, Harriet Corvol, Viviane Balloy, Olivier Terrier, Loic Guillot

Front Immunol 2021 Vol. 12 Pages 714027 In the coronavirus disease 2019 (COVID-19) health crisis, one major challenge is to identify the susceptibility factors of severe acute respiratory...
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BOCCARA Franck

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November 14 - 2020

Role of adipose tissues in osteoarthritis (Équipe Berenbaum) Natalia Zapata-Linares, Florent Eymard, Francis Berenbaum, Xavier Houard

Curr Opin Rheumatol 33 (2021): 84-93 PURPOSE OF REVIEW : Epidemiologic studies reveal that the link between obesity and osteoarthritis cannot be uniquely explained by overweight-associated...
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September 16 - 2021

Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus (Équipe Dorothée) Brianne M. Bettcher, Malu G. Tansey, Guillaume Dorothée, Michael T. Heneka

Nat Rev Neurol. 2021 Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates that pathological alterations in...
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BOISSAN Mathieu

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June 13 - 2021

Letter to the editor: Serum anti-Abeta antibodies in cerebral amyloid angiopathy (Équipe Dorothée) Yannick Chantran, Jean Capron, Diana Doukhi, Johanna Felix, Mélanie Feroul, Florian Kruse, Thomas Chaigneau, Guillaume Dorothée, Thibault Allou, Xavier Ayrignac, Zina Barrou, Thomas de Broucker, Corina Cret, Guillaume Turc, Roxane Peres, Anne Wacongne, Marie Sarazin, Dimitri Renard, Charlotte Cordonnier, Sonia Alamowitch, Pierre Aucouturier

Autoimmun Rev. 2021;20(8):102870
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BONNIN Agnès

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February 03 - 2021

Glial cells and adaptive immunity in frontotemporal dementia with tau pathology (Équipe Dorothée) Iain J. Hartnell, David Blum, James A.R. Nicoll, Guillaume Dorothée, Delphine Boche

Brain. 2021 Neuroinflammation is involved in the aetiology of many neurodegenerative disorders including Alzheimer's disease, Parkinson's disease and motor neuron disease. Whether...
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BORDBAR Sima

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May 17 - 2021

Performance of Next-Generation Sequencing for the Detection of Microsatellite Instability in Colorectal Cancer With Deficient DNA Mismatch Repair (Équipe Duval) Toky Ratovomanana, Romain Cohen, Magali Svrcek, Florence Renaud, Pascale Cervera, Aurélie Siret, Quentin Letourneur, Olivier Buhard, Pierre Bourgoin, Erell Guillerm, Coralie Dorard, Rémy Nicolle, Mira Ayadi, Mehdi Touat, Franck Bielle, Marc Sanson, Philippe Le Rouzic, Marie-Pierre Buisine, Guillaume Piessen, Ada Collura, Jean-Francois Fléjou, Aurélien de Reynies, Florence Coulet, François Ghiringhelli, Thierry André, Vincent Jonchère, Alex Duval

Gastroenterology 161 (2021): 814-826 e7 BACKGROUND & AIMS : Next-generation sequencing (NGS) was recently approved by the United States Food and Drug Administration to detect...
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BORDE Chloé

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January 09 - 2021

Cholangiopathy aggravation is caused by VDR ablation and alleviated by VDR-independent vitamin D signaling in ABCB4 knockout mice (Équipe Housset) Ester Gonzalez-Sanchez, Haquima El Mourabit, Marion Jager, Marie Clavel, Sophie Moog, Javier Vaquero, Tatiana Ledent, Axelle Cadoret, Jérémie Gautheron, Laura Fouassier, Dominique Wendum, Nicolas Chignard, Chantal Housset

Biochim Biophys Acta Mol Basis Dis. 2021;1867(4):166067 BACKGROUND & AIMS : Cholangiopathies are chronic liver diseases in which damaged cholangiocytes trigger a proinflammatory and...
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BORELAND William

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February 09 - 2021

Low-phospholipid-associated cholelithiasis syndrome: Prevalence, clinical features, and comorbidities (Équipe Housset ) Dong, Catherine, Bertrand Condat, Magalie Picon-Coste, Yves Chrétien, Pascal Potier, Béatrice Noblinski, Lionel Arrivé, Marie-Pierre Hauuy, Véronique Barbu, Anware Maftouh, Farid Gaouar, Karima Ben Belkacem, Chantal Housset, Raoul Poupon, David Zanditenas, Olivier Chazouillères, Christophe Corpechot

JHEP Rep. 2021;3(2):100201 Background & Aims : Low-phospholipid-associated cholelithiasis (LPAC) syndrome, a rare genetic form of intrahepatic cholelithiasis in adults, is still poorly...
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August 04 - 2021

EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence (Équipe Housset / Équipe Fève) Jérémie Gautheron, Christophe Morisseau, Wendy K. Chung, Jamila Zammouri, Martine Auclair, Geneviève Baujat, Émilie Capel, Célia Moulin, Yuxin Wang, Jun Yang, Bruce D. Hammock, Barbara Cerame, Franck Phan, Bruno Fève, Corinne Vigouroux, Fabrizio Andreelli, Isabelle Jéru

Elife. 2021;10. Epoxide hydrolases (EHs) regulate cellular homeostasis through hydrolysis of epoxides to less-reactive diols. The first discovered EH was EPHX1, also known as mEH. EH...
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BOUCHAMA Lyes

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September 01 - 2021

TFH cells in systemic sclerosis (Équipe Mohty) Pauline Beurier, Laure Ricard, Deborah Eshagh, Florent Malard, Lama Siblany, Olivier Fain, Mohamad Mohty, Béatrice Gaugler, Arsène Mekinian

cells in systemic sclerosis. J Transl Med 19 (2021): 375 Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis with progression to internal organs, vascular...
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August 12 - 2021

Weak immunogenicity of SARS-CoV-2 vaccine in patients with hematologic malignancies (Équipe Mohty) Florent Malard, Béatrice Gaugler, Joël Gozlan, Lucie Bouquet, Djeneba Fofana, Lama Siblany, Deborah Eshagh, Olivier Adotevi, Caroline Laheurte, Laure Ricard, Rémy Dulery, Nicolas Stocker, Zoé van de Wyngaert, Alexis Genthon, Anne Banet, Mara Memoli, Souhila Ikhlef, Simona Sestilli, Anne Vekhof, Eolia Brissot, Zora Marjanovic, Yannick Chantran, Nancy Cuervo, Éric Ballot, Laurence Morand-Joubert, Mohamad Mohty

Blood Cancer J 11 (2021): 142 This study evaluated the safety and immunogenicity of BNT162b2 vaccine in patients with hematological malignancies. Antibodies blocking spike binding to...
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BOULOUSSA Hedi

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July 21 - 2021

Impact of gut fungal and bacterial communities on the outcome of allogeneic hematopoietic cell transplantation (Équipe Mohty) Florent Malard, Aonghus Lavelle, Giorgia Battipaglia, Béatrice Gaugler, Rémy Dulery, Eolia Brissot, Clémence Mediavilla, Sarah Jegou, Nathalie Rolhion, Tounes Ledraa, Razan Mohty, Harry Sokol, Mohamad Mohty

Mucosal Immunol 14 (2021): 1127-1132 Patients receiving allogeneic hematopoietic cell transplantation (alloHCT) were previously shown to display a bacterial gut dysbiosis; however, limited...
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BOUMENDIL Ariane

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March 19 - 2021

Let's reconstitute microbiota diversity (Équipe Mohty) Florent Malard, Mohamad Mohty

Blood 137 (2021): 1442-1444
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Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients (Équipe Mohty) Florent Malard, Anne Vekhoff, Simona Lapusan, Françoise Isnard, Évelyne D'incan-Corda, Jérôme Rey, Colombe Saillard, Xavier Thomas, Sophie Ducastelle-Lepretre, Étienne Paubelle, Marie-Virginie Larcher, Clément Rocher, Christian Recher, Suzanne Tavitian, Sarah Bertoli, Anne-SophieMichallet, Lila Gilis, Pierre Peterlin, Patrice Chevallier, Stéphanie Nguyen, Émilie Plantamura, Lilia Boucinha, Cyrielle Gasc, Mauricette Michallet, Joël Dore, Ollivier Legrand, Mohamad Mohty

Nat Commun 12 (2021): 3084 Acute myeloid leukemia (AML) intensive chemotherapy combined with broad-spectrum antibiotics, leads to gut microbiota dysbiosis promoting pathological conditions...
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July 30 - 2021

Regulatory B cell imbalance correlates with Tfh expansion in systemic sclerosis (Équipe Mohty) Laure Ricard, Florent Malard, Sébastien Rivière, Charlotte Laurent, Olivier Fain, Mohamad Mohty, Béatrice Gaugler, Arsène Mekinian

Clin Exp Rheumatol 39 Suppl 131 (2021): 20-24 OBJECTIVES : Systemic sclerosis (SSc) is an autoimmune disease with fibrosis, microangiopathy and immune dysfunction. B cell abnormalities...
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March 10 - 2021

Venetoclax does not impair activated T-cell proliferation (Équipe Mohty) Bone Marrow Transplant 56 (2021): 1740-1742

Bone Marrow Transplant 56 (2021): 1740-1742
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BOUTROS Rita Maria

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July 20 - 2021

Screening of patients born small for gestational age with the Silver-Russell syndrome phenotype for DLK1 variants (Équipe Netchine) Aurélie Pham, Marie-Laure Sobrier, Éloïse Giabicani, Marilyne Le Jules Fernandes, Delphine Mitanchez, Frédéric Brioude, Irène Netchine

Eur J Hum Genet (2021) Silver-Russell syndrome (SRS) is a rare imprinting disorder associated with prenatal and postnatal growth retardation. Loss of methylation (LOM) on chromosome 11p15...
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St. Antoine Hospital

INSERM
Kourilsky Building
34 rue Crozatier - 75012 Paris
France

Sorbonne Université Medicine
Saint-Antoine Site
27 rue Chaligny - 75012 Paris
France

+(33)1 49 28 46 00
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