Search result

October 30 - 2017

Thèse : Yuanhui LIU – Rôles de la clathrine et de SMAP1 dans la signalisation et le trafic intracellulaire des récepteurs de la famille ErbB dans les carcinomes hépatocellulaires directeur : Françoise PRAZ

(Équipe Praz - mandature précédente) Les carcinomes hépatocellulaires (CHC) sont la troisième cause de décès par cancer dans le monde, avec plus...

Learn more

September 16 - 2021

Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus (Équipe Dorothée) Brianne M. Bettcher, Malu G. Tansey, Guillaume Dorothée, Michael T. Heneka

Nat Rev Neurol. 2021 Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates that pathological alterations in...

Learn more

February 16 - 2017

Thèse : Émilien LOEUILLARD — Régulation des fonctions des myofibroblastes portaux par le stress du réticulum endoplasmique directrices : Axelle CADORET, Chantal HOUSSET

(Équipe Housset) La fibrose hépatique est la conséquence de toutes les maladies chroniques du foie et se caractérise par un dépôt excessif de matrice...

Learn more

BEURIER Pauline

Learn more

June 13 - 2021

Letter to the editor: Serum anti-Abeta antibodies in cerebral amyloid angiopathy (Équipe Dorothée) Yannick Chantran, Jean Capron, Diana Doukhi, Johanna Felix, Mélanie Feroul, Florian Kruse, Thomas Chaigneau, Guillaume Dorothée, Thibault Allou, Xavier Ayrignac, Zina Barrou, Thomas de Broucker, Corina Cret, Guillaume Turc, Roxane Peres, Anne Wacongne, Marie Sarazin, Dimitri Renard, Charlotte Cordonnier, Sonia Alamowitch, Pierre Aucouturier

Autoimmun Rev. 2021;20(8):102870

Learn more

November 01 - 2017

Thèse : Renato MICELLI LUPINACCI – Caractérisation anatomo-clinique et phénotypique des adénocarcinomes pancréatiques avec instabilité des microsatellites directrice : Magali SVRECK

(Équipe Duval)

Learn more

BEYDON Nicole

Learn more

February 03 - 2021

Glial cells and adaptive immunity in frontotemporal dementia with tau pathology (Équipe Dorothée) Iain J. Hartnell, David Blum, James A.R. Nicoll, Guillaume Dorothée, Delphine Boche

Brain. 2021 Neuroinflammation is involved in the aetiology of many neurodegenerative disorders including Alzheimer's disease, Parkinson's disease and motor neuron disease. Whether...

Learn more

March 03 - 2017

Thèse : Camille VATIER – Traitement par leptine recombinante dans les syndromes lipodystrophiques génétiques: effets sur le métabolisme glucido-lipidique directrice : Corinne VIGOUROUX

(Équipe Fève) Leptin deficiency, which correlates with the decreased amount of body fat, was shown to contribute to lipodystrophy-associated metabolic complications. Recombinant...

Learn more

BIGOT Jeanne

Learn more

May 17 - 2021

Performance of Next-Generation Sequencing for the Detection of Microsatellite Instability in Colorectal Cancer With Deficient DNA Mismatch Repair (Équipe Duval) Toky Ratovomanana, Romain Cohen, Magali Svrcek, Florence Renaud, Pascale Cervera, Aurélie Siret, Quentin Letourneur, Olivier Buhard, Pierre Bourgoin, Erell Guillerm, Coralie Dorard, Rémy Nicolle, Mira Ayadi, Mehdi Touat, Franck Bielle, Marc Sanson, Philippe Le Rouzic, Marie-Pierre Buisine, Guillaume Piessen, Ada Collura, Jean-Francois Fléjou, Aurélien de Reynies, Florence Coulet, François Ghiringhelli, Thierry André, Vincent Jonchère, Alex Duval

Gastroenterology 161 (2021): 814-826 e7 BACKGROUND & AIMS : Next-generation sequencing (NGS) was recently approved by the United States Food and Drug Administration to detect...

Learn more

October 02 - 2017

Thèse : Hualin WANG – Modification de l'épissage alternatif dans la pathogenèse de la maladie hépatique directeur: Patrick SOUSSAN

(Équipe Housset)

Learn more

January 09 - 2021

Cholangiopathy aggravation is caused by VDR ablation and alleviated by VDR-independent vitamin D signaling in ABCB4 knockout mice (Équipe Housset) Ester Gonzalez-Sanchez, Haquima El Mourabit, Marion Jager, Marie Clavel, Sophie Moog, Javier Vaquero, Tatiana Ledent, Axelle Cadoret, Jérémie Gautheron, Laura Fouassier, Dominique Wendum, Nicolas Chignard, Chantal Housset

Biochim Biophys Acta Mol Basis Dis. 2021;1867(4):166067 BACKGROUND & AIMS : Cholangiopathies are chronic liver diseases in which damaged cholangiocytes trigger a proinflammatory and...

Learn more

BILIC Stéphane

Learn more

February 09 - 2021

Low-phospholipid-associated cholelithiasis syndrome: Prevalence, clinical features, and comorbidities (Équipe Housset ) Dong, Catherine, Bertrand Condat, Magalie Picon-Coste, Yves Chrétien, Pascal Potier, Béatrice Noblinski, Lionel Arrivé, Marie-Pierre Hauuy, Véronique Barbu, Anware Maftouh, Farid Gaouar, Karima Ben Belkacem, Chantal Housset, Raoul Poupon, David Zanditenas, Olivier Chazouillères, Christophe Corpechot

JHEP Rep. 2021;3(2):100201 Background & Aims : Low-phospholipid-associated cholelithiasis (LPAC) syndrome, a rare genetic form of intrahepatic cholelithiasis in adults, is still poorly...

Learn more

BINVIGNAT Marie

Learn more

August 04 - 2021

EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence (Équipe Housset / Équipe Fève) Jérémie Gautheron, Christophe Morisseau, Wendy K. Chung, Jamila Zammouri, Martine Auclair, Geneviève Baujat, Émilie Capel, Célia Moulin, Yuxin Wang, Jun Yang, Bruce D. Hammock, Barbara Cerame, Franck Phan, Bruno Fève, Corinne Vigouroux, Fabrizio Andreelli, Isabelle Jéru

Elife. 2021;10. Epoxide hydrolases (EHs) regulate cellular homeostasis through hydrolysis of epoxides to less-reactive diols. The first discovered EH was EPHX1, also known as mEH. EH...

Learn more

BIVAS Irène

Learn more

September 01 - 2021

TFH cells in systemic sclerosis (Équipe Mohty) Pauline Beurier, Laure Ricard, Deborah Eshagh, Florent Malard, Lama Siblany, Olivier Fain, Mohamad Mohty, Béatrice Gaugler, Arsène Mekinian

cells in systemic sclerosis. J Transl Med 19 (2021): 375 Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis with progression to internal organs, vascular...

Learn more

BLAISE Régis

Learn more

August 12 - 2021

Weak immunogenicity of SARS-CoV-2 vaccine in patients with hematologic malignancies (Équipe Mohty) Florent Malard, Béatrice Gaugler, Joël Gozlan, Lucie Bouquet, Djeneba Fofana, Lama Siblany, Deborah Eshagh, Olivier Adotevi, Caroline Laheurte, Laure Ricard, Rémy Dulery, Nicolas Stocker, Zoé van de Wyngaert, Alexis Genthon, Anne Banet, Mara Memoli, Souhila Ikhlef, Simona Sestilli, Anne Vekhof, Eolia Brissot, Zora Marjanovic, Yannick Chantran, Nancy Cuervo, Éric Ballot, Laurence Morand-Joubert, Mohamad Mohty

Blood Cancer J 11 (2021): 142 This study evaluated the safety and immunogenicity of BNT162b2 vaccine in patients with hematological malignancies. Antibodies blocking spike binding to...

Learn more

BLANCHET Alice

Learn more

July 21 - 2021

Impact of gut fungal and bacterial communities on the outcome of allogeneic hematopoietic cell transplantation (Équipe Mohty) Florent Malard, Aonghus Lavelle, Giorgia Battipaglia, Béatrice Gaugler, Rémy Dulery, Eolia Brissot, Clémence Mediavilla, Sarah Jegou, Nathalie Rolhion, Tounes Ledraa, Razan Mohty, Harry Sokol, Mohamad Mohty

Mucosal Immunol 14 (2021): 1127-1132 Patients receiving allogeneic hematopoietic cell transplantation (alloHCT) were previously shown to display a bacterial gut dysbiosis; however, limited...

Learn more

BLANCHET-DEVERLY Sarah

Learn more

March 19 - 2021

Let's reconstitute microbiota diversity (Équipe Mohty) Florent Malard, Mohamad Mohty

Blood 137 (2021): 1442-1444

Learn more

BLONDEAU Bertrand

Learn more

Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients (Équipe Mohty) Florent Malard, Anne Vekhoff, Simona Lapusan, Françoise Isnard, Évelyne D'incan-Corda, Jérôme Rey, Colombe Saillard, Xavier Thomas, Sophie Ducastelle-Lepretre, Étienne Paubelle, Marie-Virginie Larcher, Clément Rocher, Christian Recher, Suzanne Tavitian, Sarah Bertoli, Anne-SophieMichallet, Lila Gilis, Pierre Peterlin, Patrice Chevallier, Stéphanie Nguyen, Émilie Plantamura, Lilia Boucinha, Cyrielle Gasc, Mauricette Michallet, Joël Dore, Ollivier Legrand, Mohamad Mohty

Nat Commun 12 (2021): 3084 Acute myeloid leukemia (AML) intensive chemotherapy combined with broad-spectrum antibiotics, leads to gut microbiota dysbiosis promoting pathological conditions...

Learn more

BOCCARA Franck

Learn more

July 30 - 2021

Regulatory B cell imbalance correlates with Tfh expansion in systemic sclerosis (Équipe Mohty) Laure Ricard, Florent Malard, Sébastien Rivière, Charlotte Laurent, Olivier Fain, Mohamad Mohty, Béatrice Gaugler, Arsène Mekinian

Clin Exp Rheumatol 39 Suppl 131 (2021): 20-24 OBJECTIVES : Systemic sclerosis (SSc) is an autoimmune disease with fibrosis, microangiopathy and immune dysfunction. B cell abnormalities...

Learn more