Latest publications

Publication of various scientific studies

May 28 - 2022

Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes (Équipe Gautheron/Housset / Fève)

BMC Med. 2022 Mar 28;20(1):95 BACKGROUND : Thymidine phosphorylase (TP), encoded by the TYMP gene, is a cytosolic enzyme essential for the nucleotide salvage pathway. TP catalyzes the...
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May 18 - 2022

(99m)Tc-NTP 15-5 is a companion radiotracer for assessing joint functional response to sprifermin (rhFGF-18) in a murine osteoarthritis model (Équipe Berenbaum)

Sci Rep 2022; 12: 8146 With the emergence of disease modifying osteoarthritis drugs (DMOAD), imaging methods to quantitatively demonstrate their efficacy and to monitor osteoarthritis...
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May 11 - 2022

Human CD4+/CD8alpha+ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation (Équipe Seksik-Sokol)

JCI Insight 2022 Faecalibacterium prausnitzii (F. prausnitzii), a dominant bacterium of the human microbiota, is decreased in patients with inflammatory bowel diseases (IBD) and exhibits...
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April 29 - 2022

Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis (Équipe Berenbaum)

Front Immunol 2022; 13: 842538 Introduction : Osteoarthritis (OA) is a whole-joint disease characterized by a low-grade inflammation that is involved in both cartilage degradation and...
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April 02 - 2022

Dental pulp stem cells as a promising model to study imprinting diseases (Équipe Netchine)

  PInt J Oral Sci 2022; 14: 19 arental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting diseases are...
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March 15 - 2022

Targeting the GLP-1/GLP-1R axis to treat osteoarthritis: A new opportunity? (Équipe Berenbaum)

J Orthop Translat 2022; 32: 121-129 Osteoarthritis (OA) is a degenerative joint disease affecting millions of people worldwide. In OA, chondrocytes, synovial cells and other joint cells...
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March 14 - 2022

WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells (Équipe Sabbah)

Cancers (Basel) 2022; 14 Vasculogenic mimicry (VM) formed by aggressive tumor cells to create vascular networks connected with the endothelial cells, plays an important role in breast...
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March 09 - 2022

SLC6A14 Impacts Cystic Fibrosis Lung Disease Severity via mTOR and Epithelial Repair Modulation (Équipe Corvol)

Front. Mol. Biosci. Cystic fibrosis (CF), due to pathogenic variants in CFTR gene, is associated with chronic infection/inflammation responsible for airway epithelium alteration and lung...
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March 05 - 2022

Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer's disease (Équipes Dorothée / Seksik - Sokol)

Mol Neurodegener 2022 Vol. 17 Issue 1 Pages 19 BACKGROUND : The implication of gut microbiota in the control of brain functions in health and disease is a novel, currently emerging...
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March 02 - 2022

Gut Microbiota Reprogramming f Tryptophan Metabolism During Pregnancy Shapes Host Insulin Resistance (Équipe Seksik - Sokol)

Gastroenterology 2022
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Kourilsky Building
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France

Sorbonne Université Medicine
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France

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