Latest publications

Publication of various scientific studies

June 10 - 2022

IGF2: Development, Genetic and Epigenetic Abnormalities (Équipe Netchine)

Cells 2022 Vol. 11 Issue 12 Pages 1886 In the 30 years since the first report of parental imprinting in insulin-like growth factor 2 (Igf2) knockout mouse models, we have learnt much about...
Learn more
June 09 - 2022

3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors (Équipe Seksik-Sokol)

Sci Rep 2022; 12: 9440 In the gut ecosystem, microorganisms regulate group behaviour and interplay with the host via a molecular system called quorum sensing (QS). The QS molecule...
Learn more
June 09 - 2022

Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level (Équipe Berenbaum)

Nanoscale 2022; 14: 8691-8708 The extracellular matrix (ECM) of articular cartilage is a three-dimensional network mainly constituted of entangled collagen fibrils and interfibrillar...
Learn more
June 02 - 2022

Consequences of the Hsp110DE9 mutation in tumorigenesis and the 5-fluorouracil-based chemotherapy response in Msh2-deficient mice (Équipe Duval)

Cell Mol Life Sci 2022; 79: 332 Heat shock proteins (HSPs) play oncogenic roles in human tumours. We reported a somatic inactivating mutation of HSP110 (HSP110DE9) in mismatch...
Learn more
June 01 - 2022

Fecal microbiota and bile acids in IBD patients undergoing screening for colorectal cancer (Équipe Seksik/Sokol)

Gut Microbes 2022; 14: 2078620 Due to the potential role of the gut microbiota and bile acids in the pathogenesis of both inflammatory bowel disease (IBD) and sporadic colorectal cancer, we...
Learn more
May 28 - 2022

Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes (Équipe Gautheron/Housset / Fève)

BMC Med. 2022 Mar 28;20(1):95 BACKGROUND : Thymidine phosphorylase (TP), encoded by the TYMP gene, is a cytosolic enzyme essential for the nucleotide salvage pathway. TP catalyzes the...
Learn more
May 18 - 2022

(99m)Tc-NTP 15-5 is a companion radiotracer for assessing joint functional response to sprifermin (rhFGF-18) in a murine osteoarthritis model (Équipe Berenbaum)

Sci Rep 2022; 12: 8146 With the emergence of disease modifying osteoarthritis drugs (DMOAD), imaging methods to quantitatively demonstrate their efficacy and to monitor osteoarthritis...
Learn more
May 11 - 2022

Human CD4+/CD8alpha+ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation (Équipe Seksik-Sokol)

JCI Insight 2022 Faecalibacterium prausnitzii (F. prausnitzii), a dominant bacterium of the human microbiota, is decreased in patients with inflammatory bowel diseases (IBD) and exhibits...
Learn more
April 29 - 2022

Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis (Équipe Berenbaum)

Front Immunol 2022; 13: 842538 Introduction : Osteoarthritis (OA) is a whole-joint disease characterized by a low-grade inflammation that is involved in both cartilage degradation and...
Learn more
April 02 - 2022

Dental pulp stem cells as a promising model to study imprinting diseases (Équipe Netchine)

  PInt J Oral Sci 2022; 14: 19 arental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting diseases are...
Learn more
St. Antoine Hospital

INSERM
Kourilsky Building
34 rue Crozatier - 75012 Paris
France

Sorbonne Université Medicine
Saint-Antoine Site
27 rue Chaligny - 75012 Paris
France

+(33)1 49 28 46 00
Getting to St-Antoine
This site uses cookies and gives you control over what you want to enable Accept all Personalize