Latest publications

Publication of various scientific studies

February 27 - 2022

Impact of Collagen Crosslinking on Dislocated Human Shoulder Capsules-Effect on Structural and Mechanical Properties (Équipe Berenbaum)

Int J Mol Sci 2022; 23 Classical treatments of shoulder instability are associated with recurrence. To determine whether the modification of the capsule properties may be an alternative...

February 27 - 2022

Gremlin-1 and BMP-4 Overexpressed in Osteoarthritis Drive an Osteochondral-Remodeling Program in Osteoblasts and Hypertrophic Chondrocytes (Équipe Berenbaum)

Int J Mol Sci 2022; 23 Osteoarthritis (OA) is a whole joint disease characterized by an important remodeling of the osteochondral junction. It includes cartilage mineralization due to...

February 26 - 2022

Factors Predisposing the Response to Lumacaftor/Ivacaftor in People with Cystic Fibrosis (Équipe Corvol)

J Pers Med 2022; 12 Lumacaftor/ivacaftor (LUMA-IVA) therapy is prescribed to people with cystic fibrosis (pwCF) homozygous for the Phe508del-CFTR variant to restore CFTR protein function....

February 26 - 2022

Impact of the Ileal Microbiota on Surgical Site Infections in Crohn's Disease: A Nationwide Prospective Cohort (Équipe Seksik - Sokol)

J Crohns Colitis 2022 BACKGROUND : Surgery is performed in 50-70% of Crohn's disease (CD) patients, and its main risk is surgical site infection (SSI). The microbiota has been extensively...

February 10 - 2022

MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression (Équipe Gautheron/Housset)

Cells 2022 Vol. 11 Issue 4 ABCB4, is an adenosine triphosphate-binding cassette (ABC) transporter localized at the canalicular membrane of hepatocytes, where it mediates phosphatidylcholine...

January 28 - 2022

Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis (Équipe Berenbaum)

Sci Rep 2022 Vol. 12 Issue 1 Pages 1567 Osteoarthritis (OA) is a common disabling disease worldwide, with no effective and safe disease-modifying drugs (DMOAD) in the market. However,...

December 07 - 2021

Flagellin From Pseudomonas aeruginosa Modulates SARS-CoV-2 Infectivity in Cystic Fibrosis Airway Epithelial Cells by Increasing TMPRSS2 Expression (Équipe Corvol)

Front Immunol 2021 Vol. 12 Pages 714027 In the coronavirus disease 2019 (COVID-19) health crisis, one major challenge is to identify the susceptibility factors of severe acute respiratory...

October 12 - 2021

Risk factors for Pseudomonas aeruginosa airway infection and lung function decline in children with cystic fibrosis (Équipe Corvol)

J Cyst Fibros. 2021 Background Cystic fibrosis (CF) lung disease is characterised by recurrent Pseudomonas aeruginosa (Pa) infections, leading to structural lung damage and decreased...

September 25 - 2021

Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells (Équipe Sabbah)

Leukemia (2021) Myeloma is characterized by bone lesions, which are related to both an increased osteoclast activity and a defect in the differentiation of medullary mesenchymal stem cells...

September 16 - 2021

Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus (Équipe Dorothée)

Nat Rev Neurol. 2021 Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates that pathological alterations in...
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France

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