Latest publications

Publication of various scientific studies

February 03 - 2021

Glial cells and adaptive immunity in frontotemporal dementia with tau pathology (Équipe Dorothée)

Brain. 2021 Neuroinflammation is involved in the aetiology of many neurodegenerative disorders including Alzheimer's disease, Parkinson's disease and motor neuron disease. Whether...
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January 09 - 2021

Cholangiopathy aggravation is caused by VDR ablation and alleviated by VDR-independent vitamin D signaling in ABCB4 knockout mice (Équipe Housset)

Biochim Biophys Acta Mol Basis Dis. 2021;1867(4):166067 BACKGROUND & AIMS : Cholangiopathies are chronic liver diseases in which damaged cholangiocytes trigger a proinflammatory and...
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December 17 - 2020

Anti-Inflammatory Effects of Analogues of N-Acyl Homoserine Lactones on Eukaryotic Cells (Équipe Seksik - Sokol)

Int J Mol Sci. 2020;21(24) BACKGROUND : Since acyl-homoserine lactone (AHL) profiling has been described in the gut of healthy subjects and patients with inflammatory bowel disease (IBD),...
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December 15 - 2020

Insights from the genetic characterization of central precocious puberty associated with multiple anomalies (Équipe Netchine)

Hum Reprod. 2021 Jan 25;36(2):506-518 STUDY QUESTION : Is there an (epi)genetic basis in patients with central precocious puberty (CPP) associated with multiple anomalies that unmasks...
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December 11 - 2020

Introduction to host microbiome symbiosis in health and disease (Équipe Mohty)

Mucosal Immunol. 2020 Humans share a core intestinal microbiome and yet human microbiome differs by genes, species, enterotypes (ecology), and gene count (microbial diversity). Achievement...
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December 11 - 2020

The differentiation of prehypertrophic into hypertrophic chondrocytes drives an OA-remodeling program and IL-34 expression (Équipe Berenbaum)

Osteoarthritis Cartilage 29 (2021): 257-268 OBJECTIVES : We hypothesize that chondrocytes from the deepest articular cartilage layer are pivotal in maintaining cartilage integrity and that...
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December 05 - 2020

Gut microbiota-derived metabolites as central regulators in metabolic disorders (Équipe Seksik - Sokol)

Gut. 2020 Metabolic disorders represent a growing worldwide health challenge due to their dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact with...
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December 02 - 2020

Tryptophan Metabolism as a Pharmacological Target (Équipe Seksik - Sokol)

Trends Pharmacol Sci. 2020 L-Tryptophan is an essential amino acid required for protein synthesis. It undergoes an extensive and complex metabolism along several pathways, resulting in many...
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November 14 - 2020

Role of adipose tissues in osteoarthritis (Équipe Berenbaum)

Curr Opin Rheumatol 33 (2021): 84-93 PURPOSE OF REVIEW : Epidemiologic studies reveal that the link between obesity and osteoarthritis cannot be uniquely explained by overweight-associated...
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October 27 - 2020

The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption (Équipe Seksik - Sokol)

Tissue Barriers. 2020;8(4):1832877 The intestine is home to the largest microbiota community of the human body and strictly regulates its barrier function. Tight junctions (TJ) are major...
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France

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France

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