Latest publications

Publication of various scientific studies

June 06 - 2024

The path to next-generation disease-modifying immunomodulatory combination therapies in Alzheimer's disease (Équipe Dorothée)

Nat Aging. 2024 Jun;4(6):761-770 The cautious optimism following recent anti-amyloid therapeutic trials for Alzheimer's disease (AD) provides a glimmer of hope after years of...

May 31 - 2024

The procoagulant signature of cancer cells drives brin network formation in tumor microenvironment and impacts its quality. Implications in cancer cell migration and the resistance to anticancer agents (Équipe Sabbah)

Thromb Res. 2024 Jun;238:172-183. doi: 10.1016/j.thromres.2024.04.015. Epub 2024 Apr 17 Fibrin Clot Shields from Cancer Cells: A Barrier to Treatment and Schaffold for Migration Our...

April 05 - 2024

Identification of Cellular Protein Targets of a Half-Sandwich Iridium(III) Complex Reveals Its Dual Mechanism of Action via Both Electrophilic and Oxidative Stresses (Équipe Prunier)

J Med Chem. 2024 Apr 25;67(8):6189-6206 Identification of intracellular targets of anticancer drug candidates provides key information on their mechanism of action. Exploiting the...

April 04 - 2024

Perinatal features of children with Silver-Russell syndrome due to 11p15 loss of methylation (Equipe Netchine)

Front Pediatr. 2024 Apr 4;12:1367433 Background : A diagnosis of Silver–Russell syndrome (SRS), a rare imprinting disorder responsible for foetal growth restriction, is...

March 29 - 2024

Features of cryptococcosis among 652 HIV-seronegative individuals in France: a cross-sectional observational study (2005-2020) (Équipe Seksik/Sokol)

Clin Microbiol Infect. 2024 Mar 29:S1198-743X(24)00162-9 OBJECTIVES : We aimed to describe features and outcomes of cryptococcosis among HIV-seronegative individuals in a large...

March 07 - 2024

Molecular epidemiology of Candida africana isolates collected from vagina swabs in French Guiana (Équipe Seksik/Sokol)

Med Mycol. 2024 Mar 7;62(3):myae016 Previous molecular studies have shown that Candida africana corresponds to the clade 13 of Candia albicans. It has been mostly involved in...

March 07 - 2024

[Antimicrobial peptides: A new alternative for the treatment of aspergillosis] (Équipe Seksik/Sokol)

Rev Mal Respir. 2024 Apr;41(4):283-288 Aspergillus fumigatus is the predominant fungal species causing pulmonary aspergillosis. The present-day anti-aspergillosis arsenal is limited,...

November 14 - 2023

Adipocyte glucocorticoid receptor activation with high glucocorticoid doses impairs healthy adipose tissue expansion by repressing angiogenesis (Équipe Fève)

Diabetes. 2023 Nov 14:db230165. doi: 10.2337/db23-0165 In Human, glucocorticoids (GC) are commonly prescribed because of their anti-inflammatory and immunosuppressive properties....

June 01 - 2023

Prediction of response to immune checkpoint blockade in patients with metastatic colorectal cancer with microsatellite instability (Team Duval)

Ann Oncol. 2023 Aug;34(8):703-713 BACKGROUND : Mismatch repair-deficient (dMMR) tumors displaying microsatellite instability (MSI) represent a paradigm for the success of immune...

January 08 - 2023

Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases (Équipe Gautheron/Housset)

Int J Mol Sci. 2023 Jan 8;24(2):1236 ABCB4 (ATP-binding cassette subfamily B member 4) is a hepatocanalicular floppase involved in biliary phosphatidylcholine (PC) secretion. Variations in...
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