Latest publications

Publication of various scientific studies

March 04 - 2018

Mucosa-associated microbiota dysbiosis in colitis associated cancer (Équipe Seksik/Sokol)

Gut Microbes. 2018;9(2):131-42 Gut microbiota dysbiosis has been associated with inflammatory bowel diseases (IBD). In colorectal cancer, the gut microbiota has also been recognized as...
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March 01 - 2018

FAM13A is a modifier gene of cystic fibrosis lung phenotype regulating rhoa activity, actin cytoskeleton dynamics and epithelial-mesenchymal transition (Équipes Corvol, Prunier)

J Cyst Fibros. 2018;17(2):190-203 Background : Cystic fibrosis (CF) lung disease severity is highly variable and dependent on several factors including genetic modifiers. Family with...
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March 01 - 2018

The extracellular domain of Her2 in serum as a biomarker of breast cancer (Équipe Prunier)

Lab Invest. 2018;98(6):696-707 Breast cancer is a major health problem worldwide. In ~15% of breast cancers, the epidermal growth factor receptor HER2, a transmembrane protein, is...
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March 01 - 2018

Glycerolipid analysis during desiccation and recovery of the resurrection plant Xerophyta humilis (Bak) Dur and Schinz (Équipe Seksik/Sokol)

Plant Cell Environ. 2018;41(3):533-47 Xerophyta humilis is a poikilochlorophyllous monocot resurrection plant used as a model to study vegetative desiccation tolerance. Dehydration imposes...
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February 16 - 2018

The NDPK/NME superfamily: state of the art (Équipe Prunier)

Lab Invest. 2018;98(2):164-74 Nucleoside diphosphate kinases (NDPK) are nucleotide metabolism enzymes encoded by NME genes (also called NM23). Given the fact that not all NME-encoded...
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February 01 - 2018

Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation (Équipe Prunier)

Cancer Res. 2018;78(3):659-70 Preoperative radiotherapy (RT) is a mainstay in the management of rectal cancer, a tumor characterized by desmoplastic stroma containing cancer-associated...
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February 01 - 2018

Cholesterol trafficking and raft-like membrane domain composition mediate scavenger receptor class B type 1-dependent lipid sensing in intestinal epithelial cells (Équipe Seksik/Sokol)

Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863(2):199-211 Scavenger receptor Class B type 1 (SR-B1) is a lipid transporter and sensor. In intestinal epithelial cells, SR-B1-dependent...
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January 29 - 2018

Expert consensus document: Clinical and molecular diagnosis, screening and management of Beckwith-Wiedemann syndrome: an international consensus statement. (Équipe Netchine)

Nat Rev Endocrinol. 2018;14(4):229-49 Beckwith–Wiedemann syndrome (BWS), a human genomic imprinting disorder, is characterized by phenotypic variability that might include overgrowth,...
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December 09 - 2017

Chromosomal rearrangements in the 11p15 imprinted region: 17 new 11p15.5 duplications with associated phenotypes and putative functional consequences (Équipe Netchine)

Med Genet. 2018;55(3):205-13 Background : The 11p15 region contains two clusters of imprinted genes. Opposite genetic and epigenetic anomalies of this region result in two distinct growth...
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August 10 - 2017

Genetic disruption of the oncogenic HMGA2–PLAG1–IGF2 pathway causes fetal growth restriction (Équipe Netchine)

Genet Med. 2018;20(2):250-8 Purpose : Fetal growth is a complex process involving maternal, placental and fetal factors. The etiology of fetal growth retardation remains unknown in many...
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Kourilsky Building
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France

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France

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