Latest publications

Publication of various scientific studies

October 22 - 2018

Mixed signals from the cell's antennae: primary cilia in cancer (Équipe Seksik/Sokol)

EMBO Rep. 2018;19(11) Primary cilia (PC) are antenna-like organelles that protrude from most mammalian cells. They are essential for the regulation of several signaling pathways such as...

October 08 - 2018

Endoplasmic reticulum stress induces inverse regulations of major functions in portal myofibroblasts during liver fibrosis progression (Équipe Housset)

Biophys Acta Mol Basis Dis. 2018;1864(12):3688-96 Portal myofibroblasts (PMF) form a sub-population of highly proliferative and proangiogenic liver myofibroblasts that derive from portal...

October 01 - 2018

Card9 mediates susceptibility to intestinal pathogens through microbiota modulation and control of bacterial virulence (Équipe Seksik/Sokol)

Gut. 2018;67(10):1836-44 Objective : In association with innate and adaptive immunity, the microbiota controls the colonisation resistance against intestinal pathogens. Caspase recruitment...

September 12 - 2018

Modern-day environmental factors in the pathogenesis of osteoarthritis (Équipe Berenbaum)

Nat Rev Rheumatol. 2018;14(11):674-81 The prevalence of osteoarthritis (OA) is rising for reasons that are not fully understood. In this Opinion article, we review the possibility that OA...

September 11 - 2018

Postprandial bile acid levels in intestine and plasma reveal altered biliary circulation in chronic pancreatitis patients (Équipe Seksik/Sokol)

J Lipid Res. 2018;59(11):2202-13 Bile acid (BA) secretion and circulation in chronic pancreatitis (CP) patients with exocrine pancreatic insufficiency (EPI) were investigated by...

August 29 - 2018

Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota (Équipe Seksik/Sokol)

PLoS One. 2018;13(8):e0202587 Background and Aims : N-acyl homoserine lactones (AHLs), which are autoinducer quorum-sensing molecules involved in the bacterial communication network, also...

August 02 - 2018

Thyrocyte-specific deletion of insulin and IGF-1 receptors induces papillary thyroid carcinoma-like lesions through EGFR pathway activation (Équipe Holzenberger)

Int J Cancer. 2018;143(10):2458-69 Insulin and insulin-like growth factor (IGF)-1 signaling in the thyroid are thought to be permissive for the coordinated regulation by thyroid-stimulating...

August 01 - 2018

Diagnosis and management of postnatal fetal growth restriction (Équipe Netchine)

Best Pract Res Clin Endocrinol Metab. 2018;32(4):523-34 Fetal growth restriction (FGR) can result from multiple causes, such as genetic, epigenetic, environment, hormonal regulation, or...

July 25 - 2018

MFN2-associated lipomatosis: Clinical spectrum and impact on adipose tissue (Équipe Fève)

J Clin Lipidol. 2018;12(6):1420-35 Background : Multiple symmetric lipomatosis (MSL) is characterized by upper-body lipomatous masses frequently associated with metabolic and neurological...

July 18 - 2018

Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice (Équipe SeksikSokol)

Nat Commun. 2018;9(1):2802 Dietary lipids favor the growth of the pathobiont Bilophila wadsworthia, but the relevance of this expansion in metabolic syndrome pathogenesis is poorly...
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France

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