Thesis : Jérémy Augustin – Characterization of the immune tumor microenvironment of resected hepatocellular carcinomas
January 01 - 2020
directed by Patrick Soussan
The objective is to characterize the immune infiltration of hepatocellular carcinoma (HCC) and establish a global immunoscore that will be correlated to serum expression of the markers studied and to clinicalopathological and molecular data of hepatocellular carcinoma (HCC). We will also develop this immunolabelling on an immunocompetent mouse model of HCC. We will evaluate the impact of these profiles on clinical progression. Our work will eventually allow us to evaluate the efficacy of new therapeutic combinations of HCC.