Biochim Biophys Acta Mol Basis Dis. 2017;1863(7):1699-708
Nuclear receptors (NR), the largest family of transcription factors, control many physiological and pathological processes. To gain...
PLoS One. 2017;12(6):e0179913
Induced pluripotent stem cells hold great potential to produce unlimited amount of differentiated cells as cellular source for regenerative medicine but also...
Diabetes. 2017;66(6):1470-8
Activation of thermogenic beige adipocytes has recently emerged as a promising therapeutic target in obesity and diabetes. Relevant human models for beige...
Gut. 2017;66(6):1039-48
Objective : The bacterial intestinal microbiota plays major roles in human physiology and IBDs. Although some data suggest a role of the fungal microbiota in IBD...
Sci Rep. 2017;7(1):1749
WISP1 (Wnt1-inducible signaling pathway protein-1, also known as CCN4) is a member of the CCN family able to mediate cell growth, transformation and survival in a...
J Med Genet. 2017;54(6):413-6
Background : Type-2 familial partial lipodystrophy (FPLD2) is a rare autosomal dominant lipodystrophic disorder due to mutations in LMNA encoding lamin A/C, a...
Ann Rheum Dis. 2017;76(6):1142-8
Objectives : Compared with subcutaneous adipose tissue (SCAT), infrapatellar fat pad (IFP), the main knee intra-articular adipose tissue (IAAT), has an...
Curr Opin Rheumatol. 2017;29(2):214-22
Purpose of review : Interest in the metabolic syndrome-associated osteoarthritis phenotype is increasing. Here, we summarize recently published...
Hepatology. 2017;65(2):560-70
ABCB4 (MDR3) is an adenosine triphosphate (ATP)-binding cassette (ABC) transporter expressed at the canalicular membrane of hepatocytes, where it mediates...
Mol Metab. 2017;6(1):61-72
Objective : Intestinal glucose absorption is orchestrated by specialized glucose transporters such as SGLT1 and GLUT2. However, the role of GLUT2 in the...
PLoS One. 2017;12(1):e0170083
Nutrition during the perinatal period programs body growth. Growth hormone (GH) secretion from the pituitary regulates body growth and is controlled by Growth...
FASEB J. 2017;31(4):1531-46
NME1 (nonmetastatic expressed 1) gene, which encodes nucleoside diphosphate kinase (NDPK) A [also known as nonmetastatic clone 23 (NM23)-H1 in humans and NM23-M1...
Nat Rev Rheumatol. 2016;12(11):669-83
Alarmins (also known as danger signals) are endogenous molecules that are released to the extracellular milieu after infection or tissue damage....
